S4

Additional requirements concerning carriage under controlled temperatures

Maintenance of the prescribed temperature is essential for safe carriage. In general, there shall be:

thorough

inspection of the transport unit prior to loading;

instructions

to the carrier about the operation of the refrigeration system, including a list of the

suppliers of coolant available en route;

procedures

to be followed in the event of loss of control;

regular

monitoring of operating temperatures; and

availability

of a back-up refrigeration system or spare parts.

The temperature of the air space within the transport unit shall be measured by two independent

sensors and the output shall be so recorded that temperature changes are readily detectable.

The temperature shall be checked every four to six hours and logged.

If the control temperature is exceeded during carriage, an alert procedure shall be initiated involving

any necessary repairs to the refrigeration equipment or an increase in the cooling capacity (e.g. by

adding liquid or solid coolant). There shall also be frequent checking of the temperature and

preparations for implementation of the emergency procedures. If the emergency temperature (see also

2.2.41.1.17 and 2.2.52.1.15 to 2.2.52.1.18) is reached, the emergency procedures shall be set in

operation.

NOTE: This provision S4 does not apply to substances referred to in 3.1.2.6 when substances are

stabilized by the addition of chemical inhibitors such that the SADT is greater than 50 °C. In this

latter case, temperature control may be required under conditions of carriage where the temperature

may exceed 55 °C.